Preview REPORT Cannabis Extracts in Germany 2021-2025

Table of Contents Executive Summary ................................................................................................................................4 GLOSSARY...............................................................................................................................................6 I List of abbreviations .............................................................................................................................7 II List of Tables........................................................................................................................................8 III List of Figures .....................................................................................................................................9 Information- and data sources .............................................................................................................10 Introduction .........................................................................................................................................13 1. What is the significance of Cannabis extracts in Cannabis therapy? ................................................14 2. Full spectrum extracts ......................................................................................................................14 2.1 Designer-Extracts ....................................................................................................................14 2.2 Place of terpenes in Cannabis extracts ...................................................................................15 3. Pharmacokinetics and pharmacodynamics of Cannabis extracts .....................................................16 4. Forms of application of Cannabis extracts........................................................................................17 4.1 Oral Application ......................................................................................................................17 4.2 Vaporisation via vaporisers.....................................................................................................18 5. Production methods for Cannabis extracts ......................................................................................18 5.1 CO 2 -Extraction ........................................................................................................................19 5.2 Ethanol-Extraction ..................................................................................................................20 5.3 Butan- and Propan-Extraction ................................................................................................20 5.4 Ultrasound-Extraction.............................................................................................................21 6. Regulation of Cannabis extracts .......................................................................................................22 6.1 Relevant laws and regulation in the Cannabis market ............................................................24 6.1.1 The narcotics permit § 3 BtMG............................................................................................24 6.1.2 The import permit § 72 AMG and § 11 BtMG......................................................................25 6.1.3 The wholesale authorisation § 52a AMG.............................................................................25 6.1.4 The manufacturing authorisation, section 13 AMG.............................................................26 7. Cannabis extracts in the pharmacy ..................................................................................................26 7.1. DAC/NRF Recipes with Cannabis extracts ..............................................................................26 7.2 Special PZNs with reference to Cannabis extracts ..................................................................26 7.3 Billing and reimbursement of Cannabis extracts ....................................................................27 7.4 DAB Monograph – Cannabis Extract .......................................................................................28 7.5 Identity check of Cannabis extracts in the pharmacy .............................................................28 8. Suppliers of Cannabis extracts in Germany ......................................................................................29 8.1 Production facilities for Cannabis extracts in Germany ..........................................................29