Flyer Check, Phase-III Portfolio

8 Point range according to the 6 categories I Transparency in the indication 0 to 10 points max. 10 points II Availability of guidelines 0 to 10 points max. 10 points III Extent of Unmet Medical Need 0 to 20 points max. 20 points IV Economic pressure in the indication - 10 to 20 points max. 20 points V Study situation, outcomes, additional benefit - 7 to 82 points max. 82 points VI Achievable reimbursement price 0 to 10 points max. 10 points --------------------------------------------------------------------------------------------------------------------------------------------------- Total max. 152 Points Result Up to 40 points - No chance product Optimization too complex 41 to 80 points - Low potential "Problem Child", but can be optimized with high effort 81 to 120 points - Medium potential Optimization possible with reasonable effort 121 to 152 points - High potenzial Little potential for improvement * Basically, it should be noted that this scoring model requires continuous further empirical validation to ensure sufficient robustness. Scoring relations for the Phase III assessment and outcome The scores range from the negative range to well into the positive range. The maximum score is 152 points and the minimum achievable score is - 17 points. The actual evaluation and classification of the Phase III candidates is done in 40 - point incre- ments. We have limited ourselves to 4 outcome categories in this assessment for reasons of practicality. The two middle categories are the categories that require management attention, because there are opportunities for optimization here. The lowest category with the fewest points requires courage to make the appropriate decisi- on.